Abiraterone Androgen Antagonist

High quality Abiraterone CAS 154229-19-3 Androgen antagonist Prostate cancer treatment drugs powder Abiraterone is a chemical compound in the steroid group approved as a drug for hormone...
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Product Details

High quality Abiraterone CAS 154229-19-3 Androgen antagonist Prostate cancer treatment drugs powder


Abiraterone is a chemical compound in the steroid group approved as a drug for hormone therapy and for the treatment of castration-resistant prostate cancer in the EU. Abiraterone is the most effective form of the prodrug abiraterone acetate and is well orally bioavailable.


Basic details:

Product name: Abiraterone

CAS No.:154229-19-3

Other Names:17-(3-Pyridyl)androsta-5,16-dien-3beta-ol

MF:C24H31NO

Place of Origin:ShenZhen, China (Mainland)

Type:Antineoplastic Agents, Endocrine System Agents

Grade Standard:Medicine Grade

Brand Name: SENDI

Model Number:SD 154229-19-3

Purity:99%min

Appearance:white solid

Density::1.14g/cm3

Boiling Point::500.2°C at 760mmHg

Flash Point::256.3°C

Refractive Index::1.605

Vapor Pressure::7.99E-11mmHg at 25°C


Abiraterone Function: 

Abiraterone is a drug used in castration-resistant prostate cancer. It is formulated as the prodrug abiraterone acetate. Abiraterone can be used as a prostate cancer drug treatment. Abiraterone is a inhibitor of CYP17. It can be used to treat CRPC.


Abiraterone is a selective inhibitor of the enzyme steroid 17α-hydroxylase (CYP17A1), which catalyzes steps in androgen (testosterone) and estrogen biosynthesis. As a result, it lowers hormone production in the testes, adrenals and prostate.


History of Abiraterone:

Since 2011, newly licensed drugs with new active substances have to undergo an "early benefit assessment" by the Federal Joint Committee (G-BA) due to § 35a SGB V (AMNOG) if the pharmaceutical manufacturer wants to obtain a higher selling price than just the fixed amount. Only if there is added value, the pharmaceutical manufacturer can negotiate a price with the umbrella association of statutory health insurance companies. This also applies to abiraterone (acetate). A first positive assessment by the Institute for Quality and Efficiency in Health Care (IQWiG) has been carried out in advance. A decision regarding the "added value" of abiraterone by the G-BA took place at the end of March 2012. According to the G-BA, the drug abiraterone acetate for a group of patients has been confirmed to have considerable added value. 


Abiraterone Specification:

Item

Specification

Result

Appearance

White crystalline powder

Complies

Related substance (HPLC)

Total impurity ≤0.5%

Max single impurity ≤0.1%

0.2%

0.06%

Odor

Characteristic

Complies

Assay

99%

99.9%

Sieve analysis

100% pass 80 mesh

Complies

Loss on Drying

Residue on Ignition

≤1.0%

≤1.0%

0.12%

0.09%

Heavy Metal

<10ppm

Complies

As

<0.1ppm

0.05ppm

Pb

<0.1ppm

0.05ppm

Cd

<0.1ppm

0.05ppm

Residual Solvents

<100ppm

Complies

Residual Pesticide

Negative

Complies

Microbiology



Total Plate Count

<1000cfu/g

Complies

Yeast & Mold

<100cfu/g

Complies

E.Coli

Negative

Complies

Salmonella

Negative

Complies

HPLC:

1533267631(1).jpg


 

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1.For whatever questions about us or our products you may have, do let us know and you can be assured we reply you in details with 24 hours and to your satisfaction.
2.Customized design is avaliable , OEM&ODM are welcomed.
3.Warmly welcome your visit in our company if available

 

Purchase Guide
1. Lead Time: Within 12hours after you payment
2. Delivery Time: 3-7 days door to door
3. Packing: Super discreet (hundreds to choose from)
4. Shipping: DHL / TNT / UPS / HKEMS / FedEx / etc. 
5. Tracking number: Available after parcel deliver out. 
6. After-sales service: 24/7 online

 

Payment Terms:

We accept the following 4 kinds of payment:

 

1. Bank Transfer

--------------Suitable for all orders, Safe and convenient.

2. Western Union or Money Gram

--------------Suitable for Small orders, less than USD 2000.

3. Bitcoin

-------------- convenient .

4. T/T 100% Advance

--------------Donot worry about bulk order risk. (More than USD 10000).


Quality Guarantee:

Because products are enterprise standard, always we will send typical samples (usually 10g) for your testing by FEDEX/DHL/EMS.

 

** If the quality is confirmed by you, we insist on batch sample confirmation after your commercial order.

 

** If your testing result is different from us. We hope to exchange and unify the testing mothod, until the quality is confirmed by you.  We also insist on batch sample confirmation after your commercial order.

 

Suggestion:

Please kindly check the packages after you receive the goods, if you got wrong products/ quality problem/ short quantity, please get back to us as priority. Please note that you need to send us pictures of the defective items concerning this, and we will consider to replace or refund accordingly.

 

Package and Storage

Package:

(1)1kg/bag (1kg net weight, 1.2kg gross weight, packed in an aluminum foil bag; Outer: paper carton; Inner: double-layer PE)

(2)5kg/bag (5kg net weight, 5.2kg gross weight, packed in an aluminum foil bag; Outer: paper carton; Inner: double-layer PE)

(3)10kg/drum (10kg net weight, 12kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 310mm high, 400mm diameter)

(4)25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 350mm diameter)

(5)Customized package is available.

 

Storage:

(1)Stored in a cool and dry well-closed container and in ventilated area,

(2)kept away from moisture and strong light or high temperature.
(3)Two years under well storage situation and stored away from direct sun light.

5 (2).jpg

 

About price: Due to we have our own factory,we'll provide our bottom price.please contact us! 

 

Packing, Delivery and Payment terms:

After your payment, we will send product within 3-5 days, our after-sales staff will give you full details of the delivery, also they will be at your service after you receive and test the goods. 


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