Estrogen Hormone Diethylstilbestrol (DES) Powder

Female Hormone Steroids Powder Diethylstilbestrol CAS 56-53-1 / CAS 6898-97-1 DES Diethylstilbestrol (DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized...
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Female Hormone Steroids Powder Diethylstilbestrol CAS 56-53-1 / CAS 6898-97-1 DES


Diethylstilbestrol (DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized in 1938. It is also classified as an endocrine disruptor. Human exposure to DES occurred through diverse sources, such as dietary ingestion from supplemented cattle feed and medical treatment for certain conditions, including breast and prostate cancers.

From about 1940 to 1971, DES was given to pregnant women in the mistaken belief it would reduce the risk of pregnancy complications and losses.

Diethylstilbestrol Mainly used for estrogen lowly disease and hormonal balance due to a disorder functional bleeding, amenorrhoea, also can be used for stillbirth before induced labor, in order to improve the layer of uterine muscle oxytocin sensitivity.

Product Name:Diethylstilbestrol
Synonyms:LABOTEST-BB LT00233101;DIETHYLSTILBESTEROL;DOMESTROL;GRAFESTROL;ESTROSYN;FONATOL;ALPHA;ALPHA,ALPHA'-DIETHYL-(E)-4,4'-STILBENEDIOL
CAS:56-53-1
MF:C18H20O2
MW:268.35
EINECS:200-278-5
Product Categories:Miscellaneous Biochemicals;Intermediates & Fine Chemicals;Pharmaceuticals;STILBESTROL
Mol File:56-53-1.mol


Product Description:

In 1971, DES was shown to cause a rare vaginal tumor in girls and women who had been exposed to this drug in utero. The United States Food and Drug Administration subsequently withdrew DES from use in pregnant women. Follow-up studies have indicated that DES also has the potential to cause a variety of significant adverse medical complications during the lifetimes of those exposed.:)

The United States National Cancer Institute recommends women born to mothers who took DES undergo special medical exams on a regular basis to screen for complications as a result of the drug. Individuals who were exposed to DES during their mothers' pregnancies are commonly referred to as "DES daughters" and "DES sons".
Application
A synthetic, nonsteroidal estrogen. Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.


CoA :


Items

Specification

Results

Appearance

the colorless crystal or white crystal powder

almost white crystalline powder

Identification

1) positive reaction

complies


2) the main peak retention time of test solution should comply with working standard

complies


3) IR spectrum conform to the reference

complies

Acid basicity

neutrality is reacted

complies

Melting point

169-172oC

169-170oC

Loss on drying

≤0.5%

0.2%

Organic volatile impurities

conform

complies

Sulphated ash

≤0.1%

0.04%

Assay (C18H20O2)

99-103%

99%



Medical Uses:
 
DES has been used in the past for the following indications:
 
1. Recurrent miscarriage in pregnancy
2. Hormone replacement therapy for menopausal symptoms such as hot flashes and vaginal atrophy
3. Hormone replacement therapy for hypoestrogenism (e.g., gonadal dysgenesis, premature ovarian failure, and after oophorectomy)
4. Postpartum lactation suppression to prevent or reverse breast engorgement
5. Gonorrheal vaginitis (discontinued following the introduction of the antibiotic penicillin)
6. Prostate cancer and breast cancer
7. Prevention of tall stature in tall adolescent girls
8. As an emergency postcoital contraceptive
9. Court sanctioned Chemical castration for men convicted of sex-related crimes


Our advantages:

Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.
 
Payment Method: Western Union,Money Gram,T/T.Bitcoin.

Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.
 
Discreetly Packing: Safe and professional disguised package can be guaranteed.
 
Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of powder per month.

High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. 

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