Fulvestrant Faslodex Antiestrogen Anti Breast Cancer

1, Fulvestrant/ Faslodex Profile: Product Name: Fulvestrant Alias: Faslodex Chemical Name: (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol CAS#: 129453-61-8 MF: C32H47F5O3S MW: 606.77 Chemical structure: Appearance: White to off-white powder Assay (on...
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Product Details

1, Fulvestrant/ Faslodex Profile:
 
Product Name: Fulvestrant

Alias: Faslodex

Chemical Name: (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol

CAS#: 129453-61-8
MF: C32H47F5O3S
MW: 606.77

Chemical structure:

Fulvestrant Structure
Appearance: White to off-white powder

Assay (on anhydrous basis) : 98.9%

Standard: Enterprise standard (we also make USP standard Fulvestrant powder which is a little more expensive)

Method: By HPLC & IR

Melting point: 104-106°C
Storage temp.: 2-8°C

Solubility DMSO: >5 mg/ml

Routes of administration: Intramuscular injection

Half life: 40 days

Usage: Antiestrogen; A novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).

 

2, Applications of Fulvestrant/ Faslodex: 

 

Fulvestrant (trade name Faslodex) is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy. It is given by injection into a muscle.

 

Fulvestrant is a selective estrogen receptor degrader (SERD) and was first-in-class to be approved. It works by binding to the estrogen receptor and destabilizing it, causing the cell's normal protein degradation processes to destroy it.
Fulvestrant was approved for medical use in the United States in 2002.

 

Faslodex is liquid that is given once a month as an injection into a muscle, usually at your doctor's office. Women usually get Faslodex as long as it is effectively treating the cancer.


Benefits of Faslodex
Research has shown that Faslodex works as well as or better than Arimidex (chemical name: anastrozole), an aromatase inhibitor, in slowing or stopping the growth of metastatic (breast cancer that has spread to other parts of the body), hormone-receptor-positive breast cancer in postmenopausal women after tamoxifen has stopped working.


3, COA of Fulvestrant/ Faslodex Powder:

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4, Fulvestrant/ Faslodex Powder Picture:

 

Natural Anti Estrogen Steroids Hormones Fulvestrant Faslodex For Breast Cancer 129453-61-85


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