Guaiacol 2-Methoxyphenol Safe Organic Solvents

High Purity Synthetic Essential Spices Guaiacol 2-Methoxyphenol CAS 90-05-1 Light Yellow Liquild Guaiacol Quick Details: CAS No.:90-05-1 MF:C7H8O2 EINECS No.:201-964-7 Place of Origin:ShenZhen, China (Mainland) Type:Pharmaceutical...
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Product Details

 High Purity Synthetic Essential Spices Guaiacol 2-Methoxyphenol CAS 90-05-1 Light Yellow Liquild

Quick Details:

CAS No.:90-05-1


EINECS No.:201-964-7

Place of Origin:ShenZhen, China (Mainland)

Type:Pharmaceutical Intermediates

Grade Standard:Medicine Grade

Brand Name:SENDI

Model Number:Top Grade


Color: Light Yellow Liquild

Guaiacol Specification




Colorless to light yellow oily liquid or fused solid

UN No.






Loss on drying





No detected


Appearance: yellow liquid
Density: 1.129 g / mL at 25 ° C (lit.)
Melting point: 26-29 ° C (lit.)
Freezing point: 28 ° C
Boiling point: 205 ° C
Refractive Index: n20 / D 1.543 (lit.)
Water Solubility: 17 g / L (15 ºC)
Stability: Stable, but air and light sensitive.
Combustible. mm Hg at 25 ° C Vapor density: 4.27 (vs air)
Signal word: warning
Hazard Statements: H302; H315; H319
Cautionary Statements: P280; P301 + P312 + P330; P305 + P351 + P338; P337 + P313
Packaging level: II
Hazard category: 6.1 (b)
Customs code: 2909500000
Dangerous goods transport code: 2810
WGK Germany: 1
Hazard Classification: R22; R36 / 38
Safety Instructions: S26
RTECS number: SL7525000
Dangerous goods symbol: Xn

Product Usage
Used as analytical reagent;
For medicine, dyes and spices intermediates;
GB 2760-96 provides for the temporary use of flavors. Mainly used for the preparation of coffee, vanilla, tobacco and tobacco and other flavor. ; In medicine for the manufacture of guaiacol sulfonate, used in the perfumery industry to manufacture vanillin and artificial musk.

Guaiacol Application:

Guaiacol is a precursor to various flavorants, such as eugenol and vanillin.Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator in chemical reactions that produce oxygen. When oxygen binds to it, the complex turns yellowish brown and absorbs light maximally at about 470 nm

Synthetic essential spices
                             cinnamon series 
Product name CAS NO.FEMA
Cinnamyl alcohol104-54-12294
Methyl cinnamate103-26-42698
Isobutyl cinnamate122-67-82193
Butyl cinnamate538-65-82192
Cinnamic acid621-82-92288
Isobutyl cinnamate122-67-82193
Phenethyl cinnamate103-53-72863
Ethyl cinnamate103-36-62430
Cinnamyl acetate103-54-82293
Other series
Product name CAS NO.FEMA
Benzyl alcohol100-51-62137
Benzyl benzoate120-51-42138



Guajacol was first produced by Otto Unverdorben in 1826 by distillation of guaiacum resin. 


Guajacol is found in wood tarry red and in wood tars, the largest content is beech wood, as well as in the guaiac resin. Guaiacol is among other phenols formed by thermal or microbial degradation of lignin or phenolic acids (eg, ferulic acid) and is therefore found in many foods, especially in smoked products. Guajacol is one of the flavorings of whiskey, and it may be responsible for the cork in the wine. 


Guajacol smells smoky-medicinal and tastes sweet. The aroma wave in water is 3 ppb. With its strong hints of smoke Guajacol contributes significantly to the coffee aroma and flavor of smoked foods. The vapor pressure function results according to Antoine according to ln (P) = A- (B / (T + C)) (P in kPa, T in K) with A = 13.6745, B = 3378.850 and C = -104.630 im Temperature range from 373 to 463 K. [12] The enthalpy of evaporation at the boiling point is 52.7 kJ · mol-1. 

With iron (III) ions (ferric chloride) a green color is observed.

The methoxy group has little influence on the acidity of the phenolic OH group, the pKs value has only a very small difference to the phenol.


Guajacol is used in the fragrance industry for the production of vanillin and eugenol. In the pharmaceutical industry, it is used, for example, in medicaments as expectorant in bronchial diseases (guaifenesin). In coating technology, it is used for the "anti-skinning" properties of inks and varnishes.

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