Steroids Intermediates Hydroxyprogesterone Powder

Steroids Intermediates Hydroxyprogesterone Powder Product Name: Hydroxyprogesterone Synonyms:...
Chat Now

Product Details

Steroids Intermediates Hydroxyprogesterone Powder



Product Name: Hydroxyprogesterone

Synonyms: 17-Hydroxypregn-4-en-3,20-dione;17-hydroxy-pregn-4-ene-20-dione;17-hydroxypregn-4-ene-3,20-dione;delta(4)-pregnene-17alpha-ol-3,20-dione;gestagenogador;prodix;prodox;(8R,9S,10R,13S,14S,17R)-17-ACETYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE

CAS: 68-96-2

MF: C21H30O3

MW: 330.46

EINECS: 200-699-4


Usage And Properties

Chemical PropertiesWhite Solid

UsesProgesteron. It was isolated from adrenal glands.

Usesanticoagulant

Uses17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.


Description

1. 17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP), also known as 17α-hydroxypregn is an endogenous progestogen steroid hormone related to progesterone. It is also a chemical intermediate in the biosynthesis of many other endogenous steroids, including androgens, estrogens, glucocorticoids, andmineralocorticoids, as well as neurosteroids.

2. Under the brand name Gestageno, 17α has been marketed for clinical use in Argentina. However, esters of 17αOHP, including hydroxyprogesterone caproate, as well as hydroxyprogesterone acetate and hydroxyprogesterone heptanoateto a much lesser extent, have been used far more widely in comparison, and when "hydroxyprogesterone" is referenced from the standpoint of medical use, what is usually being referred to is actually, in general, hydroxyprogesterone caproate.

3. 17α is also the parent compound of a class of progestins referred to as the 17hydroxyprogesterone derivatives. Among others, this class of drugs includes chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, medroxyprogesterone acetate, and megestrol acetate.


Specification

itemsStandardResutls<o:p>

Description

White or almost white crystalline powder, odorless

Conforms<o:p>

Solubility


insoluble in water, solube in ether,

slightly soluble in benzene


Conforms<o:p>

Specific Optical Rotation

+58°---+64° (1% chloroform Solution)

60.3°

Melting Point

about 120 -124 ºC

123ºC

Water

≤0.1%

0.05%

Free N-Caproic Acid

≤0.58%

0.20%

Ordinary Impurities<o:p>

≤2.0%

conforms

Residual Solvents<o:p>

Methanol ≤ 3000PPM

1280PPM

Ethanol≤5000PPM

1500PPM

Dichloromethane ≤ 600PPM

80PPM

Assay

97.0%--103.0%

99.30%

Conclusion

Conforms to USP31


Application:

1) 17a-Hydroxyprogesterone caproate CAS 630-56-8 is used in women who are pregnant with a single baby, and who have delivered a baby too early (preterm) in the past. It is used to help lower the risk of having a preterm baby again. Hydroxyprogesterone is a man-made form of a female hormone (progestin).

2) 17a-Hydroxyprogesterone caproate CAS 630-56-8 is not intended to prevent preterm birth in women pregnant with more than one baby (such as twins, triplets). It is also not intended to stop active preterm labor.


Hot Tags: steroids intermediates hydroxyprogesterone powder, China, suppliers, discount, buy, bulk, pricelist, high quality, in stock

Inquiry

You Might Also Like