Beta-Nicotinamide Mononucleotide Nmn

Top quality 99%min Pure Nmn Beta-Nicotinamide Mononucleotide Powder CAS 1094-61-7 for Anti-Aging

Nicotinamide mononucleotide in human cells plays an important role in energy generation, it deals in intracellular NAD (nicotinamide adenine dinucleotide, cell energy conversion important coenzyme) synthesis, used in anti-aging, blood sugar and other health care products.

Basic details :

Product Name:Beta-nicotinamide Mononucleotide

CAS No.:1094-61-7

Other Names: Nicotinamide mononucleotide

MF:C11H15N2O8P

EINECS No.:214-136-5

Place of Origin: ShenZhen, China (Mainland)

Type:Antibiotic and Antimicrobial Agents, Antipyretic Analgesics and NSAIDs

Grade Standard:Medicine Grade

Brand Name:SENDI

Purity:99%Min

Appearance:White Powder

Assay:HPLC 99%

Shelf life:24 Months

Application:Pharmaceutical Products

Grade:Phamaceutical Grade

Beta-Nicotinamide Mononucleotide Usages:

-Nototinamide Mononucleotide belongs to Vitamin B, participating in metabolism in the body, can be used to prevent pellagra or other niacin defection disease.

-Nototinamide Mononucleotide could be used as feed / human nutrition, booth to grow and strengthen the immunity.

Nicotinamide mononucleotides play an important role in the production of human cell energy, which is involved in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide, an important coenzyme for cellular energy conversion).

β-Nicotinamide mononucleotide Application

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice.

NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. It is to be used for research only.

β-Nicotinamide mononucleotide Description

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. It is to be used for research only.

Beta-Nicotinamide Mononucleotide details:

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.

NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth. However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.

Beta-Nicotinamide Mononucleotide COA:

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