EstRADiol Valerate Female Estrogen Steroids

Estradiol Valerate Female Estrogen SteroidsProduct Name: Estradiol valerate Synonyms:...
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Product Details

Estradiol Valerate Female Estrogen Steroids




Product Name: Estradiol valerate

Synonyms: 3,5(10)-triene-3,17-diol(17-beta)-estra-17-pentanoate;atladiol;b-estradiol17-valerate;deladiol;delahormoneunimatic;delestrogen;delestrogen4x;dura-estradiol

CAS: 979-32-8

MF: C23H32O3

MW: 356.5

EINECS: 213-559-2


Specification

ItemsSpecificationResults
AppearanceWhite or almost-white,crystalline powder or colorless crystalsConform
IdentificationIRConform
Melting pointAbout 145°C147.5-149.2°C
Appearance of solutionClear and colorlessConform
SolubilityPractically insoluble in water, soluble in alcohol.Conform
Specific optical rotation+41~+47°+44.73°
Any impurity≤0.5%0.24%
Total impurity≤1.0%0.43%
Loss on drying≤1.0%0.04%
Assay97.0%~103.0%99.35%
Micron
100%≤20μm


Application:

1. Estradiol valerate is a medicine which is used in Hormone Replacement Therapy in postmenopausal women who have had a hysterectomy.

2. Estradiol valerate contains a hormone which is similar to the hormone oestrogen that is produced by the body. When women go through the menopause, levels of oestrogen become low. This leads to symptoms such as hot flushes, night sweats and dryness of the vagina. Estradiol valerate helps to replace the low levels of oestrogen which may help to relieve the symptoms of the menopause. This is known as hormone replacement therapy.

3. Estradiol valerate is a medicine which is used in Hormone Replacement Therapy in postmenopausal women who have had a hysterectomy.Estradiol valerate contains a hormone which is similar to the hormone oestrogen that is produced by the body. When women go through the menopause, levels of oestrogen become low. This leads to symptoms such as hot flushes, night sweats and dryness of the vagina. Estradiol valerate helps to replace the low levels of oestrogen which may help to relieve the symptoms of the menopause. This is known as hormone replacement therapy.


Profiles

Estradiol valerate (EV, E2V), or oestradiol valerate (BAN), is a is a semisynthetic, steroidal estrogen and an estrogen ester - specifically, the 17-valerate ester of estradiol - which is marketed in the United States, Canada, Europe, and throughout much of the rest of the world.It acts as a prodrug of estradiol, and hence, is considered to be natural, bioidentical estrogen.Along with estradiol cypionate, estradiol valerate is one of the most widely used esters of estradiol.

The medical uses of estradiol valerate are the same as those of estradiol and other estrogens. Examples of indications for the drug include hormone replacement therapy and hormonal contraception. In regards to the latter, estradiol valerate is available in combination with a progestogen as an combined estradiol-containing oral contraceptive (with dienogest) and as a combined injectable contraceptive (with hydroxyprogesterone caproate or norethisterone enanthate)


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