Oestradiol 17-heptanoate Estradiol Enanthate

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 Buy Female Hormone Estradiol Enanthate Oestradiol 17-Heptanoate CAS 4956-37-0 Powder

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Oestradiol 17-heptanoate 

Quick Details

CAS No.:4956-37-0

Other Names:Oestradiol 17-heptanoate

MF:C25H36O3

EINECS No.:4956-37-0

Place of Origin:Shenzhen, China (Mainland)

Type:Anesthetic Agents, Antineoplastic Agents, Blood System Agents, Endocrine System Agents, Vitamins, Amino Acids and Coenzymes

Grade Standard:Medicine Grade

Brand Name: SENDI

Model Number:API

Purity:99%min, 99% Estradiol Enanthate

CAS:4956-37-0

Product Name:Estradiol Enanthate

Appearance:White Powder Estradiol Enanthate

Application:Pharmaceutical Raw Intermediates

Shipment:FedEX;DHL;UPS;TNT, etc

Payment Term:T/T;Western Union;Trade Assurance

Grade:Phamaceutical Grade

Certificate:ISO9001

Package:Aluminum Bag


What is Oestradiol 17-heptanoate?

Oestradiol 17-heptanoate is a sex hormone that is present in both males and females, and is the most important form of estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and is the main hormone responsible for the fact that women are shorter than men, on average. Both the ovaries and the adrenal glands produce it.

Estradiol enanthate is an estrogen medication which is used in hormonal birth control. It is formulated in combination with dihydroxyprogesterone acetophenide (DHPA; algestone acetophenide), a progestin, and is used as a once-monthly combined injectable contraceptive. It is given by injection into muscle. 


Usage:

Ostradiol (E2 or 17β-estradiol, also oestradiol) is a sex hormone. Ostradiol is abbreviated E2 as it has twohydroxyl groups in its molecular structure. Estrone has one (E1) and estriol has three (E3). Ostradiol is about 10 times as potent as estrone and about 80 times as potent as estriol in its estrogenic effect. Except during the early follicular phase of the menstrual cycle, its serum levels are somewhat higher than that of estrone during the reproductive years of the human female. Thus it is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity. During menopause, estrone is the predominant circulating estrogen and during pregnancy estriol is the predominant circulatingestrogen in terms of serum levels. The serum levels of estradiol in males (14 - 55 pg/mL) are roughly comparable to those of postmenopausal women (< 35 pg/mL). Ostradiol in vivo is interconvertible with estrone; estradiol to estrone conversion being favored. Ostradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs, including the bones.

Product description:
 
Oestradiol 17-heptanoate is a sex hormone that is present in both males and females, and is the most important form of estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and is the main hormone responsible for the fact that women are shorter than men, on average. Both the ovaries and the adrenal glands produce it.
 
The menstrual cycle in women involves predictable variations in the levels of several hormones, with estradiol being one of them. It is involved in the ovulation process and prepares the inner lining of the uterus for implantation, should the egg be fertilized. Certain tests done on baboons and other primates have indicated that his hormone also plays a continual role in maintaining a pregnancy, helping it to last for the full gestation period.
 
As a sex hormone, it also triggers many of the developments of the reproductive system that begin in puberty. It is present throughout the reproductive years, and declines during and after menopause. This decline is precisely what causes many of the symptoms of menopause, such as hot flashes and night sweats, vaginal dryness, and the loss of bone mass that may lead to osteoporosis.


Application:                             

1-Applied in pharmaceutical field, Estradiol is used as Endocrine System Agents; 

2-Applied in Chemicial field, Estradiol can be used as Auxiliaries and Other Medicine Chemicals.

 

Specification:                             

Items

Standard

Results

Description

White crystalline powder

Complies

Identification

IR

HPLC

Reactive

Conform with standard IR

Conform with standard HPLC

Conform

Solubility

Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile

Complies

Total Impurity

max.0.5%

0.18%

Total Unspecified Impurity

max. 0.2%

0.08%

Individual unspecified impurlty

max. 0.1%

0.05%

Related compound B

max. 0.2%

0.07%

Related compound C

max. 0.2%

0.04%

Related compound D

max. 0.1%

0.05%

Related compound E

max. 0.1%

0.06%

Limit of cyclohexane

max. 0.08%

ND

Limit of ethylacetate

max. 0.1%

0.07%

Melting point

81.0~84.0°C

82.5~83.2°C

Water

max. 0.3%

0.21%

Residue on ignition

max. 0.1%

0.07%

Heavy Metals

max.0.001%

Complies

Assay(HPLC)

98.0%~102.0%

99.9%

Storage

Cool and dry

Conclusion

It complies to USP34 .



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