Bodybuilding Supplement Sarms Products SR9011

Bodybuilding Supplement CAS 1379686-30-2 Sarms Products SR9011 SARMs SR9011 is a research drug that was developed by Professor Thomas Burris of Scripps as an agonist of Rev-ErbAα with a...
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Bodybuilding Supplement CAS 1379686-30-2 Sarms Products SR9011

SARMs SR9011 is a research drug that was developed by Professor Thomas Burris of Scripps as an agonist of Rev-ErbAα with a half-maximum inhibitory concentration (IC50) = 790 nM for Rev-Erbα and IC50 = 560 nM for Rev-ErbAβ.

Product Name

Sr9011

CAS Number

1379686-30-2

Molecular Formula

C20H24ClN3O4S

Molecular Weight

437.94

Assay

99%min

Appearance

White powder

Packing

50G/bag or as your requirement

country of origin

China

MOQ

10G

Grade

Pharmaceutical Grade

Storage

Keep in cool, dry place

Application

SR9011 increase exercise endurance and loss weight.


SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.


SR9011 Main functions:

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.

Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.


Product Usage:

SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism. Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance SR9011 Not Just a "Diet" Pill.


There's no way to sugarcoat it-though many have tried-maintaining a healthy weight can be difficult. Because it's hard, many have tried "miracle" weight-loss pills and other quick fixes for something that ultimately requires a lifestyle change. Many over-the-counter diet and weigh-loss pills are unregulated and may contain dangerous ingredients. SR9011, however, isn't like appetite suppressants, laxatives, or "fat blockers." And you won't find SR9011 in the ingredient lists of protein powders or exercise supplements.


The difference between SR9009 and other diet pills is in its chemistry.SR9011 is not an appetitesuppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy.


SR9011 is one of a pair of compounds developed at TSRI by Burris and his team. The drug binds to Rev-erb,a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells. By binding to Rev-erb, SR9011 can kickstart metabolism with another pleasant side-effect: increased muscle strength.


How to Use SR9011?

In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.

In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.


FAQ:

Q1:Do you Accept Sample Order?

A: Yes, we accept small order from 1box, 5boxes and 10boxes to evaluate quality of our goods.


Q2: Is there any discount?

A: Yes, as for old customers and larger quantity, we always support with great discounts and surprise.


Q3: How to make the payment?

A: 1 Let me know the item, quantity and the destination country

2 After you confirm all details of order, pay money and give us Shipping address.

3 We can accept Western Union, Money Gram and Paypal as well.

4 We arrange the shipment at first time after receive payment and give you the tracking number

5 We will supply after-sales service after you receive parcel.


Q4:How will you deliver the goods?

A: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post, HongKong Air Post. And you also can choose your own shipping forwarder.Usually it takes about 5-12 working days to reach you


Q5:What are your packing ?

We use standard packaging to ensure that the goods will be safely passed through customs and reach your hands


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