99% MK-677 Nutrobal Ibutamoren 159752-10-0 SARM Powder Increase Muscle Bone Mass
1, MK-677 Profile:
Product Name | MK-677 |
Synonyms | Nutrobal; Ibutamoren Mesylate; MK677; MK-0677; L-163,191; Crescendo |
CAS No. | 159752-10-0 |
MF | C27H36N4O5S.CH4O3S |
MW | 624.776 |
Categories | SARMs(Selective androgen receptor modulator) |
Structure: |
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Appearance | White to yellowish crystalline powder |
Purity | >99% |
Usage | SARM bodybuilding, muscle wasting, obesity and osteoporosis treatment, increase muscle mass and bone mineral density |
2, MK-677 Applications:
Ibutamoren is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat. It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
How it Works?
Growth hormone pulse intensity can be increased through 4 possible mechanisms:
- Increasing GHRH (growth hormone releasing hormone) release.
- Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
- Reducing somatostatin release (somatostatin turns off GH release).
- Inhibiting of somatostatin receptor signaling.
Nutrobal (Mk-677) was found to work through all four of these mechanisms. After ingestion, Growth Hormone (GH) was shown to increase dose dependently, at doses starting at 5 milligrams (mgs) a day.
How can it help you? - The Best HGH Alternative!
Elevated growth hormone has literally endless list of benefits to the human body, why do you think everyone tries to get their hands on HGH? That's why Nutrobal (Mk-677) is so effective, it increases Growth Hormone and IGF-1 levels.
As the studies show, Nutrobal can be used for a number of reasons from growing muscle mass, to getting shredded. It does not compete with the levels of growth hormone one can get from exogenously administered HGH, so you can use it with hgh cycles. In fact, by using nutrobal, you can easily get amazing increases of your own natural growth hormone pulses without having to deal with annoying and painful daily HGH injections. It's like using HGH without having to inject daily.
In a multitude of studies, Nutrobal (Mk-677) increased IGF-1 levels by between 39-89%. To give you an idea of what IGF-1 does, here are some IGF-1 benefits:
- Increased Fat Oxidation (fat loss).
- Increased Muscle gains (lean mass).
- Tightening up loose skin.
- Healing old injuries.
- Healing Bones, Tendons and Ligaments.
In fact, many users report growing up to 6 lbs of lean muscle mass in 8 weeks of IGF-1 only cycles. That's an amazing result, but injecting IGF-1 daily is painful, costly and frustrating. Now, there is an oral-only alternative.
3, MK-677 Specifications (COA):
| TEST | ACCEPTANCE CRITERLA | RESULTS |
Identification | TLC | Positive |
| UV spectrum | Positive | |
| IR spectrum | Positive | |
| Characteristics | White to yellowish-white crystalline powder | Conform |
| Melting point | 32 ~ 37ºC | 33~36ºC |
| Specific optical rotation | +77°~+82° | +79.3° |
| Loss on drying | ≤0.5% | 0.15% |
| Assay | 97 ~ 103% | 99.08% |
| Free heptanoic acid | ≤0.2 % | 0.10% |
| Related substances | ≤2% | Pass |
Residual solvents(GC) | Acetone ≤100ppm | Pass |
| Methanol ≤100ppm | Pass | |
| Pyridine ≤100ppm | Pass | |
| Particle size | Pass |
