SARMs Steroids Megestrol Acetate Powder
Basic Information:
Product Name: Megestrol acetate
Synonyms: 17-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione;17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;17-alpha-acetoxy-6-dehydro-6-methylprogesterone;17alpha-Acetoxy-6-dehydro-6-methylprogesterone;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione17-acetate;5071;6-dehydro-6-methyl-17-alpha-acetoxyprogesterone;6-Dehydro-6-methyl-17alpha-acetoxyprogesterone
CAS: 595-33-5
MF: C24H32O4
MW: 384.51
EINECS: 209-864-5
Descriptions:
Megestrol is used to treat cancer of the breast or uterus. Megestrol is similar to a natural substance made by your body called progesterone.
This section contains uses of Megestrol that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use Megestrol for a condition that is listed in this section only if it has been so prescribed by your health care professional.
Megestrol may also be used to treat cancer of the ovaries or prostate. Megestrol may also be used to treat weight loss in people with certain conditions by improving their appetite.
Profiles and Functions:
Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesteronederivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropiceffects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same asmegestrol, which is a closely related but different compound.
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induceweight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
Dosage:
Megestrol acetate is available as 5 mg, 20 mg and 40 mg tablets and in oral suspensions of 125 mg/ml and 40 mg/ml. It is used at a dose of 5 mg in combination with an estrogen for contraception. Appetite stimulation is achieved with doses ranging from 400 mg to 800 mg a day. Doses used to treat cancer usually range from 40 mg to 320 mg.
In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
Dosage: Megestrol acetate is available as 5 mg, 20 mg and 40 mg tablets and in oral suspensions of 125 mg/ml and 40 mg/ml. It is used at a dose of 5 mg in combination with an estrogen for contraception. Appetite stimulation is achieved with doses ranging from 400 mg to 800 mg a day. Doses used to treat cancer usually range from 40 mg to 320 mg.
Items of analysis | Specification | Results |
Appearence | White to creamy white, tasteless, the basic no smell of the crystalline powder | white crystalline powder |
Identification | Infrared absorption (IR) | Complies |
Specific rotaion | +8.8~+12° | +11.74° |
Melting point | 213-220℃ | 214.6~218.9℃ |
Water | ≤0.5% | 0.12% |
Residual on ignition | ≤0.2% | 0.11% |
Heavy Metal | ≤0.002% | Complies |
Organic volatile impurities | Conforms to demand | Complies |
Particle size | 100%≤20μm | 100%≤20μm |
Assay | 97.0~103.0% | 99.34% |