SR9011 SARM Powder Increase Energy Fat Loss

99.2% SR9011 CAS 1379686-29-9 SARM Supplement SR-9011 Powder 1, SR9011 Profile: Product Name: SR9011 Chemical Name: SR-9011; 3-(((4-Chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide CAS No.: 1379686-29-9 Molecular Formula: C23H31ClN4O3S Molucelar Weight:...
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Product Details

99.2% SR9011 CAS 1379686-29-9 SARM Supplement SR-9011 Powder


1, SR9011 Profile:


Product Name: SR9011

Chemical Name: SR-9011; 3-(((4-Chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide

CAS No.: 1379686-29-9
Molecular Formula: C23H31ClN4O3S

Molucelar Weight: 479.03524

Molecular Structure:

Appearance: White fine powder
Purity: 99.2%
Storage: 0°C (short term), -20°C (long term), desiccated
Solubility: DMSO
Usage: Novel agonist of Rev-ErbAalpha/beta

 
2, Applications of SR9011: 

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.


SR9011 VS SR9009
The difference between SR9009 and other diet pills is in its chemistry. SR9011 is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy.




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