Enhancement Steroids Structural characteristics

- Apr 11, 2018-

Methotrexate is a modified form of dihydrotestosterone.Enhancement Steroids The difference lies in the addition of a methyl group at carbon 1, which helps to protect the hormone from liver metabolism during oral administration. The same structural modifications are also used for oral (methyl phenol) tablets. Alkylation at one site slows the hepatic metabolism of steroids during the first pass, Enhancement Steroids although far less pronounced than the c-17 alpha alkylation. Although the overall bioavailability remains much lower than the c-17 alpha alkylated oral steroids, Enhancement Steroids methyridone is sufficiently resistant to enable therapeutically beneficial blood levels. Metestosterone also has a very strong binding affinity for sex hormone binding globulin.

Metestosterone does not aromatize and is not a measurable estrogen. When this steroid is used, no anti-estrogen is needed because the drug is unlikely to induce the development of mammary glands, Enhancement Steroids water retention or other estrogen-related side effects in men.

Metestosterone is thought to act as an anti-aromatase in the body to prevent or slow the conversion of steroids to estrogen. The result is somewhat similar to anastrozole, although not so profound. The anti-estrogen properties of mestrelin are not unique, Enhancement Steroids and many other steroids demonstrate similar activity.Enhancement Steroids For example, dihydrotestosterone and tetrastone have been successfully used as therapeutics for male breast development and breast cancer due to their strong androgens and potential anti-estrogen effects. It has also been proposed that methyridone can even reduce aromatase activity in peripheral tissues where it is more resistant to estrogen conversion. Enhancement Steroids The anti-estrogen effects of all these compounds may be due to their ability to compete with other substrates for binding to aromatase. Since aromatase binds to steroids, Enhancement Steroids it cannot be changed because it is temporarily blocked from interacting with other hormones to achieve inhibitory effects.