HCG 5000iu Human Chorionic Gonadotropin

HCG (Human Chorionic Gonadotropin) raw powder HCG 5000iu peptides human growth injectable CAS 9002-61-3 Product Name: HCG Other Names: Human Chorionic Gonadotropin Purity: 99% CAS No.: 9002-61-3 Appearance: White powder...
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Product Details

HCG (Human Chorionic Gonadotropin)  raw powder HCG 5000iu peptides human growth injectable CAS 9002-61-3 Welcome to Contact Mitchell: Whatsapp +8618129984346 Email: Mitchellu88@gmail.com

Product Name: HCG

Other Names: Human Chorionic Gonadotropin

Purity: 99%

CAS No.: 9002-61-3

Appearance: White powder

Assay: 5000 IU

Usage: Help women get pregnant 


(HCG) Human chorionic gonadotropin is a glycoprotein secreted by trophoblast cells of the placenta and is composed of glycoproteins of alpha and beta dimers. Human chorionic gonadotropin (HCG) αβ is synthesized by syncytiotrophoblasts.

The molecular weight of 36,700 glycoprotein hormones, α subunit and pituitary secretion of FSH (follicle stimulating hormone), LH (LH) and TSH (TSH) are basically similar, it can cross-react with each other, and β sub-Asia The structure of the base are not similar. The structure of β-HCG is similar to that of β-LH, but the last 24 amino acid extensions are absent in β-LH.


Application:

Human chorionic gonadotropin (hCG) is a glycoprotein hormone that is normally produced first by the cells that make up the placenta, then later by the placenta during pregnancy. Its primary function is to support the pregnancy by encouraging the production of progesterone. This supports and promotes the further development of the placenta early in pregnancy. This hormone causes a rapid progesterone increase early in pregnancy, but tapers off slowly as the placenta grows enough to produce enough progesterone to support the pregnancy on its own. The glycoprotein also serves in aiding in the development of gonads in the fetus and the production of androgens by the testes of a male fetus.


Chorionic Gonadotropin is a gonad-stimulating polypeptide hormone obtained from the urine of pregnant women. Its potency is not less than 1500 USP Chorionic Gonadotropin Units in each mg, and not less than 80.0 percent and not more than 125.0 percent of the potency stated on the label.


The sales volume of our urinary products has always occupy more than 60% of the world and the chinese market. The company has recognized as “ the only and the largest manufacturer producing items from urine to the bulk drugs.” The company also product the Benzoate excipients in both Med.Grade and food grade.


The purified HCG project with high yield and high titer which use the urine of pregnant women as raw material,the purified HMG project with high yiels and high titer which use the urine of amenorrhoea women as raw meterial,and the purified UK project with high yield and high titer which use male urine as raw meterial were passed the appraisal organized by Qingdao Science Committee as “International Leading Level”.


As the material of the three projects is the urine from pregnant women and amenorrhoea women , and the male urine, all these products are changing waste into valuable. And the products use urine of pregnant women and amenorrhoea women are the drug of first choice which can treat the infertility,the product with male urine is the drug of first choice which can treat myocardial infarction. The quality of our productd conforms to USP-31,BP-2003,CP-2005. All these items were passed GMP .


As the three biological pharmaceutical products of our company were favored by the American, Germany, England, Holland, Spain, Italy, Switzerland, India, Japan, Korea, Russia, Egypt and other countries and regions,our products are Best-selling and unabated.


Concentration 

For men and non-pregnant women, the normal blood hCG level is up to 5 IU / liter. In women, after the onset of menopause, the normal value increases to as much as 10 IU / liter.  About five days after the implantation, the concentration increases. In the third week after conception, the values are still below 50 IU / liter, in the fourth week under 400 IU / liter. The maximum is reached in the 10th to 12th week with up to 230,000 IU / liter. The concentration then drops again and is towards the end of pregnancy between 5,000 and 65,000 IU / liter. Other studies describe maximum values of 289,000 IU / liter and report values between 940 and 60,000 IU / liter towards the end of pregnancy.  About 11 to 17 days after birth normal values are reached again.


The urine concentration is lower. Over-the-counter pregnancy tests usually show a positive result in the urine after 25 IU / liter. 


Function 

At the beginning of pregnancy, approximately 114 hours (mid-fifth day) after fertilization, a special form of hCG, the hyperglycosylated hCG, begins to prepare for implantation (nidation) of the blastocyst. For this purpose, some cells of the blastocyst differentiate into mononuclear cytotrophoblast cells, in which initially predominantly the hyperglycosylated hCG is formed. Through contact with the uterine endometrium (mucous membrane), some trophoblast cells differentiate and proliferate into the multinucleated syncytiotrophoblast, which subsequently produces the biologically active hCG. From these two cell forms, finally, the primary chorion with its villi develops, the early form of the infantile part of the placenta. HCG stimulates the corpus luteum in the ovary to release another hormone, progesterone, which builds up the lining of the uterus and signals to the ovaries via negative feedback to the pituitary gland that no ovulation is necessary for the next time (no further ovulation). Since pregnancy does not kill the corpus luteum, but rather maintains the release of progesterone, menstruation stops and the uterine lining built up before ovulation is loosened up. The degeneration of the corpus luteum into a cicatricially altered corpus albicans remains, it develops into a corpus luteum graviditatis.


In the first weeks of pregnancy, the hCG concentration in the blood steadily increases, about every two days, the hormone levels double. The maximum is reached approximately between the eighth and the tenth week of pregnancy. Thereafter, the hCG levels slowly decrease to basal levels that are reached shortly before the 20th week of gestation. Until the placenta is mature enough to produce the pregnancy hormone progesterone itself, the corpus luteum can continue to produce progesterone until the end of the 4th month of pregnancy.


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